The effects of Sildenafil on the heart are unknown, but it's known that the drug inhibits a biological pathway involved in controlling the stress and overgrowth of the heart. In the penis, it helps relax blood vessels and maintain an erection. It's not entirely clear how sildenafil does this, but it does act by inhibiting an enzyme called PDE5A.
In 1998, the U.S. Food and Drug Administration approved Fildena 200Mg. Initially developed to treat cardiovascular disease and high blood pressure, it was discovered by scientists at Pfizer that it could also cause penile erections. A generic version of the drug, made by Teva, entered the market in December 2017. For more doses like, Fildena 100 Mg , Fildena 25 pill